Both players will be monitored ahead of the trip to Broadhall Way, where Premier League side Newcastle succumbed in the previous round.
Noel Hunt may be available again having missed last week's 1-1 draw at home to Hull while fellow striker Shane Long should also be fine despite receiving lengthy treatment in the same match.
Midfielder Michail Antonio is expected to be in contention despite suffering from a back problem which ruled him out against the Tigers.
However, new signings Mathieu Manset, Brett Williams and Sean Morrison are all cup-tied.
The Royals made it to round four courtesy of a 1-0 win over West Brom at the Madejski Stadium.