Stephen Pearson, Mo Camara, Gary Teale, Lewin Nyatanga and Stephen Bywater have all returned to Pride Park after the conclusion of their loan spells while David Jones has recovered from a calf injury.
County will hand a late fitness test to Jay McEveley (hamstring) but Dean Leacock requires a hernia operation and misses out.
Reading winger Glen Little is rated as doubtful because of a calf injury.
Manager Steve Coppell has no other injury worries but will be without two players who have been suspended by the club.
Ibrahima Sonko and Emerse Fae are still serving two-week suspensions after refusing to play in a reserve game earlier in the month.
Teams:
Derby (from): Carroll, Moore, McEveley, Mears, Addison, Edworthy, Sterjovski, Savage, Ghaly, Lewis, Miller, Villa, Earnshaw, Todd, Beardsley, Feilhaber, Price, Camara, Teale, Pearson, Nyatanga, Bywater.
Reading (from): Hahnemann, Federici, Rosenior, Murty, de la Cruz, Ingimarsson, Duberry, Bikey, Shorey, Doyle, Oster, Harper, Matejovsky, Cisse, Hunt, Kitson, Lita, Long, Convey.